Take our online questionnaire to find out if genetic counseling is appropriate for you.

< Back to disease list

Multiple Endocrine Neoplasia

Multiple endocrine neoplasia (MEN) is part of a group of disorders that affect the body's network of hormone-producing glands (the endocrine system). Individuals with MEN are at increased risk to develop endocrine tumors. These tumors can be noncancerous (benign) or cancerous (malignant). The two major forms of multiple endocrine neoplasia are called type 1 (MEN1) and type 2 (MEN2).

Features of the condition

• MEN1
  
  • Parathyroid disease
  • Pituitary tumors
  • Other endocrine system tumors
  • Benign skin tumors (angiofibromas, collegenomas,
  • lipomas, leiomyomas)
• MEN2
  
  • Medullary thyroid cancer
  • Pheochromocytoma (adrenal gland tumor)
  • Parathyroid disease

Risk Factors

• MEN1
  • Parathyroid tumor, pituitary tumor, or other endocrine tumors when
    • More than one of these is seen in a single individual
    • These are seen in more than one family member
• MEN2
  • Medullary thyroid cancer, pheochromocytoma, and parathyroid disease when
    • More than one of these is seen in a single individual
    • These are seen in more than one family member

Genetic Tests

The following genetic tests may be appropriate based on your personal and/or family history:

• MEN1
• RET

Schedule an Appointment

To speak with a board-certified genetic counselor about your risks for this disease:

• Schedule genetic counseling appointment online
• Or call 1-800-975-4819
• Send email

Learn More

National Institutes of Health Genetics Home Reference(NIH/GHR)

American Society of Clinical Oncology: MEN1, MEN2

National Cancer Institute (NCI)